Good news! I resolved my issue of getting SpiceTools to launch the game data on my problematic desktop, but not in the way I expected....
- First thing I did was reformat the desktop with a clean install of Win 10 Pro (ver 21H1), then reinstall the game data using the provided directions. Surprisingly, I was still unable to launch the game and left with a log that looked mostly the same as before (still showing EXCEPTION ACCESS VIOLATION).
- Next, I ran windows update and downloaded all available updates. After, I ran Spice.exe again, but had the same result.
- Finally, I downloaded Lenovo's update utility (this pc is a Lenovo ThinkCentre M93p, got it on eBay for under $100) and pulled all additional driver and bios updates that weren't available from Microsoft. After the the bios install completed and the pc rebooted, I launched Spice.exe again, and to my surprise, it boots perfectly.
So, if anyone else ever comes across this post with the same issue, maybe try updating drivers and bios from your pc manufacturer. That's what ended up working for me. ¯\_(ツ)_/¯