I am new to Singe and I am having the same audio stuttering issue as many other people, but I don't have Realtek audio drivers.
I have an integrated audio card that works fine with any other software, including Daphne, but not Singe. My device manager shows no sign of Realtek stuff, under "Sound, video and game controllers" (showing hidden devices too, of course) I only see "High Definition Audio Device" and "NVIDIA High Definition Audio", both using non-Realtek up-to-date drivers. However, I also remember that this PC used to have some Realtek audio-related programs in the past when it was running Windows 7, but hasn't had them since I upgraded to Windows 10. I even searched through the registry settings but the only trace of something Realtek is related to a USB network adapter used in the past. What else could it be?
I haven't had time to try more than 3 games so far, but I noticed that while Cliffhanger and Timegal stutter (and are also non-responsive to controls), instead Conan doesn't stutter. It looks like Conan is lower resolution, so perhaps someone was right to previously point out that stuttering might be also related to HD resolution, and not just audio.
I use exclusively either USB headsets or analog jack headphones with my PC (as I haven't had loudspeakers for a while), neither of them requires drivers, and stuttering happens with both. However, if I do NOT plug any of them, Singe doesn't even start i.e. it crashes immediately. Even with Conan (which otherwise doesn't stutter and plays fine with headphones) Singe crashes immediately. This bit sounds more like a Singe bug to me, that maybe cannot handle having no audio output device available.
It feels terrible to see all these awesome works of love done to the old lasergames, and not be able to appreciate them... am I stuck with low-resolution and bugged Daphne versions forever?