What we have seen so far. The AIMTRAK, the EMS and the SINDEN (afaik) work like a mouse. This game is not tracking the mouse absolute position (at least with the current settings). It's tracking the mouse as a stick, as if it was the stick on a gamepad. Its like aiming on a first person shooter. The movement of the crosshair is relative to some sensitivity settings which are not related to your cursor absolute position on screen (or where you point with the gun).
My video above shows exactly how the mouse behaves once the game starts.
No reason to think that the Sinden will behave any different (and I have 2 preordered)